Anti-cyclic citrullinated peptide antibodies and rheumatoid factor in Rheumatoid Arthritis

نویسندگان

چکیده

Introduction: For the diagnosis of Rheumatoid Arthritis (RA), detection autoantibodies, rheumatoid factor (FR) and cyclic citrullinated peptide antibodies (APCC) are used. The presence these determines that RA is classified as seropositive or seronegative, with important implications both in clinical development prognosis disease. Objective: To assess role APCC RF RA, well its influence on establishment pharmacological treatment. Methodology: We studied 213 patients initial suspicion determinations FR APCC. Their definitive treatment established were studied. Results: 63 had a RA. 77.8% seropositive. sensitivity specificity higher compared to FR. Initially presented low diagnostic value since it was negative more than two thirds precise adjustment reference allowed use useful tool. influences choice an increased Methotrexate against other immunosuppressants patients. Conclusions: better parameters test validity RF. possibly due greater severity pathology.

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ژورنال

عنوان ژورنال: Actualidad médica

سال: 2021

ISSN: ['0365-7965', '2605-2083']

DOI: https://doi.org/10.15568/am.2021.813.or02